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Drug Information

Ofloxacin Ophthalmic drops, solution

What is this medicine?

OFLOXACIN (oh FLOKS a sin) is a quinolone antibiotic. It is used in the eye to treat bacterial infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • an unusual or allergic reaction to ofloxacin, fluoroquinolone antibiotics, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper to your eye, fingertips, or any other surface. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Your vision may blur for a few minutes. Use your doses at regular intervals. Do not use your medicine more often than directed. Finish the full course prescribed by your doctor or health care professional even if you think your condition is better.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other eye products without telling your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve in 2 to 3 days.

If you get any sign of an allergic reaction, stop using your eye product and call your doctor or health care professional.

Wear sunglasses if this medicine makes your eyes more sensitive to light.

Do not wear contact lenses while you have any signs or symptoms of an eye infection. Ask your doctor or health care professional when you can start wearing your lenses again.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • blurred vision that does not go away

  • burning, stinging, or itching of the eyes or eyelids

  • redness, swelling, or pain of the eyes or eyelids

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • temporary blurred vision

  • tearing or feeling of something in the eye

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Throw away any unused eye solution after the expiration date.


Ofloxacin Oral tablet

What is this medicine?

OFLOXACIN (oh FLOKS a sin) is a quinolone antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • arteriosclerosis

  • bone problems

  • cerebral disease

  • irregular heartbeat

  • joint problems

  • kidney disease

  • liver disease

  • myasthenia gravis

  • seizures

  • tendon problems

  • an unusual or allergic reaction to ofloxacin, fluoroquinolone antibiotics, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think your are better. Do not skip doses or stop your medicine early.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • cisapride

  • droperidol

  • some medicines for irregular heart rhythm

This medicine may also interact with the following medications:

  • antacids

  • cimetidine

  • cyclosporin

  • didanosine

  • medicines for diabetes

  • medicines for pain and swelling like ibuprofen, naproxen

  • multivitamins with minerals

  • probenecid

  • sucralfate

  • theophylline

  • warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve or get worse. Make sure you stay well hydrated while taking this medicine. Drink several glasses of fluids a day.

If you are a diabetic monitor your blood sugar carefully. If your blood sugar reading is unusual, stop taking this medicine and call your doctor for advice.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Do not treat diarrhea with over-the-counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

Avoid taking didanosine, sucralfate, antacids, or iron or zinc products within 2 hours of taking this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash or hives, swelling of the face, lips, or tongue

  • breathing problems

  • chest pain

  • confusion, nightmares or hallucinations

  • fever, chills

  • irregular heartbeat or feeling faint

  • joint, muscle or tendon pain or swelling

  • persistent headache with or without blurred vision

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • seizures

  • tremor

  • unusual pain, numbness, tingling, or weakness

  • yellowing of eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • difficulty sleeping

  • headache

  • nausea, vomiting

  • stomach upset, gas

  • unusual taste

  • vaginal irritation

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at a temperature between 15 and 30 degrees C (59 and 85 degrees F). Keep container closed tightly. Throw away any unused medicine after the expiration date.


Ofloxacin Otic drops, solution

What is this medicine?

OFLOXACIN (oh FLOKS a sin) is a quinolone antibiotic. It is used to treat bacterial ear infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • difficulty hearing

  • an unusual or allergic reaction to ofloxacin, quinolone antibiotics, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is only for use in the ear. Wash your hands with soap and water. Do not insert any object or swab into the ear canal. Gently warm the bottle by holding it in the hand for 1 to 2 minutes. Gently clean any fluid that can be easily removed from the outer ear. Lie down on your side with the infected ear up. Try not to touch the tip of the dropper to your ear, fingertips, or other surface. Squeeze the bottle gently to put the prescribed number of drops in the ear canal.

For ear canal infections, gently pull the outer ear upward and backward to help the drops flow down into the ear canal. For middle ear infections, press the skin-covered cartilage in the front part of the ear 4 times in a pumping motion to allow the drops to pass through the hole or tube in the eardrum. Keep lying down with the ear up for about 5 minutes to make sure the drops stay in the ear. Repeat the steps for the other ear if both ears are infected. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 months of age and older for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other ear products without talking to your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your ear infection does not get better in a few days. After you finish the full course of treatment, tell your doctor or health care professional if you have two or more episodes of drainage from the ear within 6 months.

It is important that you keep the infected ear(s) clean and dry. When bathing, try not to get the infected ear(s) wet. Do not go swimming unless your doctor or health care professional has told you otherwise.

To prevent the spread of infection, do not share ear products, or share towels and washcloths with anyone else.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • burning, blistering, itching, and redness

  • dizziness

  • rash

  • worsening ear pain

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • abnormal sensation in the ear

  • bad taste in mouth

  • unpleasant sensation while putting the drops in the ear

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Throw away any unused medicine after the expiration date.